在大细胞神经内分泌癌的病例中,高血症和骨转移,具有未知的初级原发性
Ekrem Yetiskul1, Jordyn Salak1, Fatema Arafa1
1Department of Internal Medicine, Staten Island University Hospital, 475 Seaview Avenue, Staten Island, New York 10305, USA.
Case reports in oncological medicine
|May 29, 2024
概括
大细胞神经内分泌癌 (LCNEC) 是一种罕见的,攻击性的癌症. 这一案例突出了LCNEC,其未知主要来源呈现为肝脏质量和高血症.
科学领域:
- 在瘤学瘤学.
- 病理学 病理学 病理学
- 放射学 放射学是一门学科.
背景情况:
- 大细胞神经内分泌癌 (LCNEC) 是一种罕见的,攻击性的恶性瘤.
- 虽然LCNEC通常起源于肺部或胃肠道,但可以在各种位置出现.
- 带有未确定的原始源的神经内分泌瘤 (NETs) 的预后较差.
研究的目的:
- 报告LCNEC的病例,其原始源不明.
- 为了说明诊断的挑战和这种病例的呈现.
主要方法:
- 一个59岁的男性患有RUQ疼痛的案例介绍.
- 诊断工作包括肝功能测试,水平,RUQ超声波,CT扫描和肝活检.
主要成果:
- 发现肝功能测试升高和严重的高血症.
- 图像检查显示了许多肝脏质量,暗示转移.
- 肝脏活检证实LCNEC与一个身份不明的原始来源.
结论:
- 即使是未知的初级病因,LCNEC也可以出现肝转移和高血症.
- 早期诊断和管理对于改善患者的治疗结果至关重要.
相关概念视频
Metastasis
5.5K
Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
5.5K
Hormones and Bone Tissue
2.7K
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
2.7K
Skeleton and Calcium Homeostasis
4.5K
Calcium is not only the most abundant mineral in bone but also the most abundant mineral in the human body. Calcium ions are needed for bone mineralization, tooth health, heart rate regulation and strength of contraction, blood coagulation, the contraction of smooth and skeletal muscle cells, and the regulation of nerve impulse conduction. The average calcium level in the blood is about 10 mg/dL. When the body cannot maintain this level, a person will experience hypo or hypercalcemia.
4.5K
Synthesis and Functions of Calcitonin
1.8K
Calcitonin, a vital polypeptide hormone, regulates calcium levels within body fluids. It is released by the parafollicular cells, also known as C cells, situated in the follicular epithelium of the thyroid gland. Calcitonin responds to fluctuations in blood calcium levels and the influence of gastrointestinal hormones like gastrin and cholecystokinin.
The exact mechanisms by which calcitonin operates in calcium homeostasis remain elusive, but its significance is evident in several vital...
The exact mechanisms by which calcitonin operates in calcium homeostasis remain elusive, but its significance is evident in several vital...
1.8K


