积极的风险分层和低风险的青素过敏脱标由抗微生物管理药剂师的药剂师
Breana N Caturano1, Lauren L Bjork1, Paola N Lichtenberger1
1Miami Veterans Affairs Healthcare System, Miami, FL, USA.
概括
对青素过敏的取消标签对于抗菌药物管理至关重要,但未得到充分利用. 大多数曾经患有青素过敏史的患者是低风险的,可以在不进行皮肤检测的情况下进行脱标,从而扩大了对护理的准入.
科学领域:
- 传染性疾病 传染性疾病
- 临床药房 临床药房
- 过敏和免疫学 过敏和免疫学
背景情况:
- 青素 (PCN) 过敏脱标是抗菌药物管理计划中的一个关键策略.
- 广泛实施PCN过敏脱标倡议面临挑战,并落后于其公认的重要性.
研究的目的:
- 评估药剂师主导的青素过敏脱标的可行性和影响.
- 确定在没有正式过敏测试的情况下符合取消标签的青素过敏史患者的比例.
主要方法:
- 药剂师领导的素过敏患者的风险分层.
- 对低风险患者实施直接的药物挑战.
- 评估脱标结果独立于过敏/免疫学服务.
主要成果:
- 大多数被评估的患者有低风险的青素过敏史.
- 这些低风险患者有资格退出标签,而不需要进行皮肤检测.
- 药剂师主导的干预措施成功扩大了对青素过敏的获取.
结论:
- 药剂师主导的青素过敏脱标,利用风险分层和药物挑战,是有效的.
- 这种方法可以独立于专业的过敏/免疫学服务来实施,改善患者获取和抗菌药物管理.
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