烟草吸入和精液参数之间的关联在患有初级和二级不孕症的男性中:一个横截面研究
ShiWei Fan1, Zeling Zhang1, HuiRu Wang1
1Reproductive Medicine Center & Department of Obstetrics and Gynecology, The First Affiliated Hospital of University of Science and Technology of China (USTC), Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Frontiers in endocrinology
|May 29, 2024
概括
烟草吸烟通过降低不育男性的精子度和运动能力,对男性生育能力产生负面影响. 戒烟对于改善精液质量和生育结果至关重要.
科学领域:
- 生殖医学 生殖医学
- 安德罗学与人类学
- 公共卫生 公共卫生
背景情况:
- 男性不孕症影响了大量寻求生殖援助的夫妇.
- 烟草吸烟是一种普遍的生活方式因素,可能对生殖健康产生不利影响.
- 了解吸烟对精子参数的具体影响对于有针对性的干预至关重要.
研究的目的:
- 调查烟草吸烟与初级和二级不孕症男性的精子参数之间的关联.
- 量化吸烟对精子质量的影响,包括不同程度的吸烟对精子质量的影响.
- 提供证据支持戒烟作为生育治疗的组成部分.
主要方法:
- 一项涉及1938年中国不育男性的横截面研究.
- 参与者被分为不吸烟者,中度吸烟者 (1-10支/天) 和重度吸烟者 (>10支/天).
- 精液参数 (精液量,度,精子总数,渐进性运动性,正常形态) 根据世卫组织2010年指导方针进行评估;用于分析,采用了后勤回归.
主要成果:
- 在初级和二级不孕症组中,吸烟与不良的精液参数有显著的相关性.
- 严重吸烟者在初级不孕症组 (P=0.01) 的精子度中位数 (59.2×10^6/ml) 与非吸烟者 (68.6×10^6/ml) 相比显著较低.
- 在二次不孕症组中的重吸烟者,与非吸烟者 (48.1%) 相比,中位数渐进性运动率 (44.7%) 显著降低 (P=0.04).
结论:
- 烟草吸烟被证明与不育男性精液参数的有害影响有关.
- 这些发现强调了将戒烟计划纳入生育治疗方案的重要性.
- 促进戒烟可以导致精液质量的大幅改善,并提高受影响男性的生育结果.
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