严重心力衰竭患者营养不良的影响
Matteo Pagnesi1, Lisa Serafini1, Mauro Chiarito2,3
1Institute of Cardiology, ASST Spedali Civili, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy.
European journal of heart failure
|May 29, 2024
概括
营养不良在严重心力衰竭 (HF) 患者中很常见,并显著增加死亡风险. 较低的体重指数和较高的尿酸预测了这一群体的营养不良.
科学领域:
- 心脏病学 心脏病学
- 营养科学 营养科学
- 老年病的医生 老年病的医生
背景情况:
- 营养不良对严重心力衰竭 (HF) 的作用尚未得到充分证实.
- 评估营养状况对于管理复杂的HF患者至关重要.
研究的目的:
- 确定严重HF患者营养不良的发病率,预测因素和预后影响.
- 为了评估营养不良和全因死亡率在这个群体之间的关联.
主要方法:
- 一个多中心的队列研究,包括510名严重的HF患者 (2020年1月 - 2021年11月).
- 使用老年营养风险指数 (GNRI) 评估营养状况;营养不良被定义为GNRI ≤98.8.
- 预测因素包括体重指数 (BMI) 和尿性 (BNP,NT-proBNP).
主要成果:
- 35.1%的患者出现营养不良 (GNRI ≤98).
- 较低的BMI和较高的尿素水平 (BNP> 685 pg/ml或NT-proBNP> 5775 pg/ml) 预测了营养不良.
- 营养不良患者的一年全因死亡率为41.1%,而营养良好患者的死亡率为22.4%.
结论:
- 营养不良在严重的HF中很普遍,并且独立地与增加的死亡风险有关.
- 较低的BMI和较高的尿酸是严重高血压患者营养不良的关键预测因素.
- 早期识别和管理营养不良对于改善心力衰竭的结果至关重要.
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