在巴西严重的COVID-19发生一年后,肺功能和生活质量
Tarciane Aline Prata1, Arnaldo Santos Leite1, Valéria Maria Augusto1
1. Universidade Federal de Minas Gerais - UFMG - Belo Horizonte (MG) Brasil.
在严重的COVID-19住院一年后,幸存者经历了呼吸不全和生活质量下降等持续症状,这表明COVID-19的影响长期存在. 进一步的后续对理解和管理这些长期影响至关重要.
科学领域:
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 严重的COVID-19 (冠状病毒疾病2019) 可能导致长期的健康问题.
- 了解严重的COVID-19的长期后果对于患者管理和公共卫生战略至关重要.
- 以前的研究已经强调了各种后COVID-19症状,但长期的肺功能和生活质量数据仍然很重要.
研究的目的:
- 评估严重COVID-19住院患者的持续症状,肺功能和生活质量.
- 为了在入院后的12个月标志上评估这些结果.
- 确定症状与肺功能和生活质量的客观测量之间的潜在相关性.
主要方法:
- 采用了横截面研究设计.
- 包括189名严重的COVID-19幸存者住院治疗在巴西贝洛霍里森特.
- 使用肺功能测试,六分钟步行测试和EQ-5D-3L问卷进行数据收集.
主要成果:
- 在住院12个月后,43%的幸存者报告呼吸障碍.
- 在呼吸障碍患者中,27%的患者表现出限制性呼吸障碍,18%的患者表现出一氧化碳 (DLCO) 扩散能力受损.
- 与没有呼吸障碍的幸存者相比,呼吸障碍与明显更严重的DLCO损伤和更差的生活质量有关.
结论:
- 在中等收入国家,严重COVID-19的幸存者面临着显著的症状负担,限制性肺部变化,以及一年后的生活质量下降.
- 这些发现强调了严重的COVID-19的长期影响,这标志着长期COVID-19的某些方面.
- 持续跟踪对于进一步描述长期COVID-19和制定有效的缓解策略至关重要.
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