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Updated: Jun 25, 2025

Constructing Cyclic Peptides Using an On-Tether Sulfonium Center
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循环和线性PEG结合物的比较

Grace E Kunkel1, Qingyang Zhou1, Joseph W Treacy1

  • 1Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, California 90095, United States.

Bioconjugate chemistry
|May 29, 2024
PubMed
概括

循环聚合物-蛋白质生物结合物为生物治疗药物提供了更好的稳定性和药理动力学. 这项研究首次证明了循环聚乙烯甘醇 (PEG) 与T4溶酶的结合,为药物开发带来了有前途的结果.

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