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Updated: Jun 25, 2025

Production of Disulfide-stabilized Transmembrane Peptide Complexes for Structural Studies
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对于分泌成分与二元体IgA相互作用的结构和生化要求

Sonya Kumar Bharathkar1, Beth M Stadtmueller1,2,3

  • 1Department of Biochemistry, University of Illinois Urbana-Champaign, Urbana, IL.

Journal of immunology (Baltimore, Md. : 1950)
|May 29, 2024
PubMed
概括

分泌IgA (SIgA) 对于粘膜免疫非常重要. 这项研究确定了分泌成分 (SC) 域D1和D3中的关键残留物,这些残留物介导了对二维IgA (dIgA) 的结合,澄清了SIgA的传输机制.

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