睡眠问题和慢性肌肉骨疼痛之间的双向关系:通过元分析进行系统审查
Nils Runge1,2,3, Ishtiaq Ahmed1, Tobias Saueressig4
1Pain in Motion Research Group (PAIN), Department of Physiotherapy, Human Physiology and Anatomy, Faculty of Physical Education & Physiotherapy, Vrije Universiteit Brussel, Brussel, Belgium.
睡眠问题增加了患慢性肌肉骨疼痛的风险. 虽然慢性疼痛也可能导致短期睡眠问题,但长期双向关系需要更多的研究.
科学领域:
- 疼痛医学 医学 疼痛医学
- 睡眠医学 睡眠医学
- 流行病学 流行病学
背景情况:
- 慢性肌肉骨疼痛和睡眠问题之间存在双向关系.
- 对这种关系的前性调查有限.
- 需要系统审查和元分析来综合现有证据.
研究的目的:
- 系统地审查和元分析睡眠问题/障碍和慢性肌肉骨疼痛之间的潜在关联.
- 评估这些关联的证据的确定性.
主要方法:
- 对前纵向队列研究的系统综述和元分析.
- 搜索了6个数据库,查找成人研究的睡眠问题/障碍和慢性肌肉骨疼痛.
- 使用Hartung-Knapp调整的随机效应元分析;使用GRADE评估证据确定性.
主要成果:
- 起初睡眠问题增加了短期 (OR 1.64) 和长期 (OR 1.39) 慢性肌肉骨疼痛的风险.
- 在基线时慢性肌肉骨疼痛增加了短期睡眠问题的风险 (OR 1.56).
- 广泛的疼痛增加了长期睡眠问题的风险 (OR 2.0);其他类别的证据不确定.
结论:
- 睡眠问题与患慢性肌肉骨疼痛的风险增加有关.
- 睡眠问题和慢性肌肉骨疼痛之间的双向关系需要进一步的前性调查.
- 对于特定的睡眠问题类别和疼痛对睡眠的长期影响的证据仍然不确定.
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