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Updated: Jun 25, 2025

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载体基因和他类药物诱导的肝毒性

Seo-A Choi1, Jung Sun Kim1, Yoon-A Park1

  • 1College of Pharmacy and Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 03760, Korea.

Cardiovascular drugs and therapy
|May 29, 2024
PubMed
概括

达丁类药物诱导的肝损伤与SLCO1B1.1.等药物载体的遗传变异有关. 特定的SLCO1B1 (有机阴离子载体聚1B1) 和ABCG2 (乳腺癌抗性蛋白) 多态性显著增加肝毒性风险,有助于个性化他类药物治疗.

关键词:
在ABCB1中,ABCB1是ABCB1.这就是ABCG2ABCG2.肝毒性 肝毒性 肝毒性药物基因组学 药物基因组学在SLCO1B1B1中,类他类药物是一种药物.

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