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Updated: Jun 25, 2025

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PM2.5对通过miR-133b-5p/EGFR/Claudin1/MUC5AC轴的气道中的粘液过分分泌的影响

Lerong Chen1, Liangliang Wu1, Xiaopeng Cheng1

  • 1Department of Respiratory, Jiangxi Provincial Chest Hospital, Nanchang 330006, Jiangxi, China.

Aging
|May 29, 2024
PubMed
概括

颗粒物 (PM2.5) 暴露降低了miR-133b-5p的调节,激活了EGFR/MAPK通路. 这导致MUC5AC的高分泌,并加剧了老鼠的呼吸道炎症.

关键词:
欧洲农业基金会 (EGFR) 是一个基金.在 MUC5ACAC 中.对于PM2.5来说,这是一个很好的例子.呼吸道炎症 呼吸道炎症在 miR-133b-5p 中使用.

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