中国老年人癌症死亡率的趋势,2005年至2035年
Meiyan Wang1, Xunli Su1, Yunhua Hu1
1Shihezi University School of Medicine, Shihezi, Xinjiang, China.
PloS one
|May 29, 2024
概括
在中国的癌症死亡率.
科学领域:
- 老年学是一门学科.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 中国人口老龄化带来了重大的健康挑战.
- 癌症是中国居民死亡和发病的主要原因之一.
- 了解老年人癌症趋势对于公共卫生战略至关重要.
研究的目的:
- 分析中国老年人口 (2005-2016年) 癌症流行病学特征.
- 确定老年人癌症死亡率的趋势和风险因素.
- 为老龄化人口提供癌症预防和治疗策略的信息.
主要方法:
- 利用来自中国癌症登记处年度报告 (2005-2016) 的60岁以上癌症死亡率数据.
- 用员工的joinpoint回归来计算趋势分析的年平均百分比变化 (AAPC).
- 应用年龄周期队列 (APC) 和贝叶斯年龄周期队列 (BAPC) 模型来评估年龄,周期和出生队列效应,并预测未来的趋势.
主要成果:
- 在老年人中,癌症总死亡率每年下降1.2% (2005-2016).
- 农村癌症死亡率高于城市,但差距缩小了;死亡率随着年龄的增长而增加.
- 肺癌是主要原因,在特定年龄组的女性中增加趋势;未来的预测显示全国下降,但城市上升.
结论:
- 尽管趋势在下降,但中国老年人癌症死亡率高于全球平均水平.
- 早期癌症查至关重要,特别是在老年男性和农村人口中.
- 需要有针对性的干预措施来解决特定人口结构中的差异和上升趋势.
相关概念视频
01:21Cancer Survival Analysis
343
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
343
02:57Targeted Cancer Therapies
7.6K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.6K
01:28Current Trends in Nursing I
1.5K
Current trends in nursing include:
1.5K
02:07Tumor Progression
6.3K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
6.3K
01:20Actuarial Approach
75
The actuarial approach, a statistical method originally developed for life insurance risk assessment, is widely used to calculate survival rates in clinical and population studies. This method accounts for participants lost to follow-up or those who die from causes unrelated to the study, ensuring a more accurate representation of survival probabilities.
Consider the example of a high-risk surgical procedure with significant early-stage mortality. A two-year clinical study is conducted,...
Consider the example of a high-risk surgical procedure with significant early-stage mortality. A two-year clinical study is conducted,...
75
02:21Cancers Originate from Somatic Mutations in a Single Cell
11.9K
Cancer arises from mutations in the critical genes that allow healthy cells to escape cell cycle regulation and acquire the ability to proliferate indefinitely. Though originating from a single mutation event in one of the originator cells, cancer progresses when the mutant cell lines continue to gain more and more mutations, and finally, become malignant. For example, chronic myelogenous leukemia (CML) develops initially as a non-lethal increase in white blood cells, which progressively...
11.9K