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在黑色素瘤中哨戒淋巴结活检前进行广泛局部切除

Michael Tassavor¹, Madalyn Bland¹, Olivia Goldenberg²

¹The Skin Cancer Center, Cincinnati, Ohio.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]

|May 29, 2024

概括

延迟粗黑色素瘤的广泛局部切除没有证据支持. 哨兵淋巴结活检可以在不影响黑色素瘤切除结果的情况下进行.

科学领域:

在瘤学瘤学.
手术瘤学手术瘤学
皮肤病学皮肤病学

背景情况:

目前的指导方针建议推迟粗黑色素瘤的广泛局部切除 (WLE),直到哨兵淋巴结活检 (SLNB) 后.
这种做法是基于这样的假设,即事先的消费税可能会损害SLNB的准确性.

研究的目的:

批判性地评价科学文献关于延迟WLE对于厚色黑色素瘤的必要性.
确定目前推迟WLE到SLNB完成的指南是否存在科学依据.

主要方法:

对现有医学文献进行了全面的叙事审查.
检查了所有相关研究,涉及WLE与厚黑色素瘤SLNB相关的时间.

主要成果:

审查没有发现任何证据表明,先前的局部切除损害了哨兵淋巴结识别.
存在关于SLNB中潜在的虚假负数的无根据的说法,原因是以前消费税中使用的大型旋转.

结论:

没有科学理由推迟粗黑色素瘤的广泛局部切除,直到哨兵淋巴结活检后.
根据现有证据,应重新评估目前关于厚黑色素瘤WLE延迟的指导方针.

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相关概念视频

Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...