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在接受干预性神经放射学手术的患者中,有效和器官剂量:一个多中心研究

Andrea D'Alessio¹, Sabina Strocchi², Federico Dalmasso³

¹Medical Physics Department, University Hospital "Maggiore della Carità", Novara, Italy.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)

|May 29, 2024

概括

脑血管造影和动脉瘤治疗的辐射剂量有很大的差异. 这项研究提供了转换因子,以估计从Kerma-Area产品 (PKA) 测量中的患者有效和器官剂量,帮助在神经干预手术中评估剂量.

科学领域:

医学物理医学物理
放射学放射学是一门学科.
辐射保护辐射保护

背景情况:

大脑血管造影和内动脉瘤治疗涉及显著的辐射暴露.
准确评估患者的辐射剂量对于优化神经干预程序的安全至关重要.
辐射剂量结构报告 (RDSR) 和蒙特卡洛模拟提供了用于剂量估计的先进方法.

研究的目的:

在接受脑血管造影和内动脉瘤治疗的成年患者中评估辐射剂量.
从克尔马区域产品 (PKA) 值确定用于估计有效剂量和器官剂量的转换因子.
评估不同血管造影设备和方案对患者辐射暴露的影响.

主要方法:

分析了77个脑部手术在三个意大利中心使用五种血管造影设备类型.
从DICOM辐射剂量结构报告 (RDSR) 提取16244次辐射事件的剂量计数据.
使用蒙特卡罗PCXMC软件计算有效剂量和器官剂量,并进行统计分析以进行中心间比较.

主要成果:

在各种程序和设备中观察到克尔马区域产物 (PKA) (14-561 Gycm2) 和有效剂量 (1.2-73.5 mSv) 的广泛变化.
确定大脑,唾液腺,口腔粘膜,甲状腺和骨是最容易暴露的器官.
确定了有效剂量的0.09 ± 0.02 mSv/Gycm2的转换因子,在中心之间通常具有一致的因子.

结论:

神经干预手术的确定的器官和有效剂量.
提供可靠的转换因子来估计从PKA测量的有效和器官剂量.
突出了最近血管造影技术的剂量降低效益.

关键词:

转换因子是指转换因子.剂量测量方法剂量测量方法有效剂量/器官剂量干预性神经放射学干预性神经放射学

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