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转录基因分析和膀癌风险评估:从铜死亡相关基因的洞察力

Xu Wang1, Long Jin1, Xiaoyu Zhang1

  • 1Department of Urology, The Second Hospital of Jilin University, Changchun 130022, PR China.

Cellular signalling
|May 29, 2024
PubMed
概括

铜与死亡相关的基因 (CRG) 影响膀癌 (BC) 的进展. 识别像LIPT1这样的关键基因和分子亚型可以改善BC风险评估和治疗策略.

关键词:
膀癌是一种癌症.铜与死亡相关的基因分子子类型 分子子类型多个omics的分析分析.风险评估模型风险评估模型

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Genetic polymorphisms in drug targets have emerged as critical determinants of interindividual variability in drug response and toxicity. Pharmacogenomic investigations increasingly focus on identifying these variations to personalize and optimize therapeutic interventions. A drug target may be a receptor, enzyme, or signaling protein involved in pharmacologic responses or disease-related pathways. While early pharmacogenetic studies focused primarily on drug metabolism, current research...