患者报告的症状事件不能充分反映心房律乱
Zameer Abedin1, Maranda Herner1, Michael Torre2
1Division of Cardiovascular Medicine, University of Utah Health, Salt Lake City, Utah.
Heart rhythm
|May 29, 2024
概括
心房动 (AF) 事件增加了症状的可能性,但与症状的相关性很差. 了解这种症状-节律相关性 (SRC) 是改善AF管理和研究的关键.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
- 医疗监测 医疗监测
背景情况:
- 前庭动 (AF) 的管理往往侧重于缓解症状.
- 门诊心电图 (AECG) 监测期间症状节律失调的程度尚不清楚.
研究的目的:
- 为了量化心房失常 (心房高心率/心房动[AT/AF]) 事件的症状节律相关性 (SRC).
- 评估影响AT/AF与患者报告的症状之间的关联因素.
主要方法:
- 来自第三级护理中心的AECG数据的回顾性队列分析.
- 包括≥7天的AECG,至少有一个AT/AF情节.
- 患者触发的症状 (呼吸短促,疲劳,心,头,昏) 与使用多变量逻辑回归的AT/AF事件一起被分析.
主要成果:
- 分析了742名具有合格AECG数据的患者.
- 总体SRC为0.39,表明相关性较差.
- AT/AF 存在增加了 ~8.3 倍的症状概率 (调整后的分析,P < .01).
- 之前的AF节律控制治疗和较低的心率与更糟糕的SRC相关 (P < .01).
结论:
- 虽然AT/AF事件提高了症状概率,但症状事件和记录的AT/AF之间存在着较差的整体相关性.
- 患者因素和先前的治疗方法显著影响SRC.
- 更好地了解SRC对于优化AF临床结果和研究严谨性至关重要.
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