在COVID-19大流行期间妊娠体重增加和新生儿生物测量:一个多中心观察队列
Mahmoud Abdelwahab1, Jessica A de Voest2, Torri D Metz3
1Departments of Obstetrics and Gynecology of The Ohio State University, Columbus, Ohio.
American journal of perinatology
|May 29, 2024
概括
在COVID-19大流行期间怀孕增加了过度妊娠体重增加 (GWG) 的风险,并降低了不充分的GWG的风险. 新生儿结局,如小 (SGA) 或大 (LGA) 妊娠年龄的婴儿保持不变.
科学领域:
- 产科和妇科 产科和妇科
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 流行病学 流行病学
背景情况:
- 由于COVID-19的流行,孕妇面临着前所未有的挑战.
- 了解其对孕产妇和新生儿健康状况的影响对于公共卫生至关重要.
- 孕期体重增加 (GWG) 和胎儿生长是怀孕健康的关键指标.
研究的目的:
- 调查COVID-19大流行期间分娩与GWG变化之间的关联.
- 评估大流行对小 (SGA) 和大 (LGA) 妊娠年龄新生儿的频率的影响.
- 为了比较流行病和流行病前分娩队伍之间的GWG和新生儿结局.
主要方法:
- 一项多中心观察队列研究比较了COVID-19大流行期间 (2020年6月至12月) 和之前 (2019年3月至12月) 的分娩情况.
- 排除标准包括多胎妊娠,胎儿异常和SARS-CoV-2阳性.
- 多变量回归分析评估了流行病暴露和结果之间的关联,重点是GWG和新生儿大小 (SGA,LGA).
主要成果:
- 这项研究分析了10,717次分娩;4,225次在疫情期间和6,492次之前.
- 疫情期间的孕妇年龄较大,更有可能患有妊娠期糖尿病.
- 在大流行期间,过度GWG更频繁 (54.9%对比53.1%),不足的GWG更少 (17.0%对比19.3%).
- 在SGA (5.4%对6.1%) 或LGA (16.0%对15.0%) 新生儿的频率上没有观察到显著差异.
结论:
- 在COVID-19大流行期间分娩与过度GWG的可能性更高有关.
- 流行病组中观察到不充分GWG的可能性较低.
- 疫情并没有显著改变SGA或LGA新生儿的频率.
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