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Updated: Jun 25, 2025

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胰岛素分泌颗粒是1型糖尿病中自抗原形成的热点

Jason Groegler1, Aïsha Callebaut2, Eddie A James2

  • 1Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

Diabetologia
|May 29, 2024
PubMed
概括

1型糖尿病涉及自身免疫性破坏胰岛素生成β细胞. 新兴的见解揭示了胰岛素分泌颗粒如何产生独特的,触发自身反应性T细胞并提供治疗点.

关键词:
这是一种自身免疫力.贝塔细胞 贝塔细胞 贝塔细胞卡特赫普辛 D D D D D D中心的宽容度是中央的宽容度.混合胰岛素类的混合胰岛素.胰岛素颗粒是什么 胰岛素颗粒新表位物 (Neoepitopes) 是一种新表位物.后翻译修改后的修改.审查 审查 审查 审查第1类糖尿病患者.

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