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Updated: Jun 25, 2025

MicroRNA-based Regulation of Picornavirus Tropism
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自然证据表明,冠状病毒的2'-O-甲基转移酶活性通过改善基质RNA结合来影响病毒病原性

Jikai Deng1, Shimin Yang1, Yingjian Li1

  • 1State Key Laboratory of Virology, RNA Institute, College of Life Sciences and Frontier Science Center for Immunology and Metabolism, Wuhan University, Wuhan, China.

Signal transduction and targeted therapy
|May 29, 2024
PubMed
概括

由于特定的残留物,SARS-CoV-2显示出比SARS-CoV更强的2'-O-MTase活性,影响病毒复制和免疫反应. 监测nsp16突变是评估病毒病原性的关键.

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