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Updated: Jun 25, 2025

Experimental Melanoma Immunotherapy Model Using Tumor Vaccination with a Hematopoietic Cytokine
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Experimental Melanoma Immunotherapy Model Using Tumor Vaccination with a Hematopoietic Cytokine

Published on: February 24, 2023

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向BCL9/BCL9L通过促进常规1型树突细胞 (cDC1) 激活和瘤透来增强抗原呈现

Fenglian He1, Zhongen Wu1, Chenglong Liu1

  • 1Department of Pharmacology, Minhang Hospital, and Key Laboratory of Smart Drug Delivery, Shanghai Engineering Research Center of Immune Therapy, School of Pharmacy, Fudan University, Shanghai, 201203, China.

Signal transduction and targeted therapy
|May 29, 2024
PubMed
概括

向B细胞淋巴瘤9和B细胞淋巴瘤9类 (BCL9/BCL9L) 增强了常规1型树突细胞 (cDC1) 的抗原呈现. 这促进了CD8+ T细胞的反应,并延迟了瘤的生长,提供了一种新的癌症免疫治疗策略.

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