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Updated: Jul 13, 2026

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骨质生成不完善型10和细胞支架是常见免疫性疾病的基础

Alan Herbert1

  • 1InsideOutBio, 42 8th Street, Charlestown, MA, USA. alan.herbert@insideoutbio.com.

Genes and immunity
|May 29, 2024
PubMed
概括

骨质发生不完善型10是由SERPINH1基因变异影响热冲击蛋白47 (HSP47) 的结果,影响原折叠和骨质细胞分化. 这些HSP47变种破坏了参与孟德尔和复杂疾病的细胞支架.

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