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Updated: Jun 25, 2025

Substrate Generation for Endonucleases of CRISPR/Cas Systems
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Published on: September 8, 2012

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通过DNA或RNA标结合激活的Cas9的转核酶活性

Jiyun Chen1, Ying Chen1, Linglong Huang1

  • 1State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, China.

Nature biotechnology
|May 29, 2024
PubMed
概括

第二种类型的CRISPR-Cas9系统表现出RuvC依赖的ssDNA和ssRNA的跨裂变. 这一发现使敏感的DNA和RNA检测平台成为可能,扩大了CRISPR-Cas应用.

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