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Updated: Jun 25, 2025

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紫外线失活的rVSV-M2e型流感疫苗可以预防H1N1流感挑战

Titus Abiola Olukitibi1,2, Zhujun Ao1,2, Hiva Azizi3

  • 1Laboratory of Molecular Human Retrovirology, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.

Frontiers in bioscience (Landmark edition)
|May 30, 2024
PubMed
概括

基于聚变蛋白 (rVSV-EΔM-tM2e) 的紫外线无活化复合囊泡性口腔炎病毒 (rVSV) 的载体显示出强大的免疫性和对流感的保护能力. 这种非活化的候选疫苗有效地引起广泛的免疫反应,并保护小鼠免受H1N1挑战.

关键词:
抗体依赖的细胞细胞毒性 (ADCC)埃博拉病毒葡萄糖蛋白是埃博拉病毒的葡萄糖蛋白.在M2的ectodomain中.紫外线无活化 紫外线无活化流感 流感 流感 流感 流感再组合囊泡性口腔炎病毒.

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