艾滋病毒药物耐药性突变的发展和新兴趋势:基于CiteSpace的文献分析
Xuannan Chen1, Xi Chen2, Yu Lai2
1Acupunture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Frontiers in microbiology
|May 30, 2024
概括
了解HIV耐药性突变至关重要,因为它们挑战治疗. 这种图书统计分析绘制了研究趋势,确定了关键贡献者和新兴主题,如下一代测序和新药疗法.
科学领域:
- 病毒学 病毒学
- 传染性疾病 传染性疾病
- 药理学 药理学是指药理学的学科.
背景情况:
- 抗逆转录病毒疗法已经将艾滋病转变为慢性疾病.
- 艾滋病毒中新出现的药物耐药性突变构成了重大的临床挑战.
- 需要对艾滋病毒耐药性突变研究进行全面分析,以指导未来的战略.
研究的目的:
- 系统地分析和可视化艾滋病毒耐药性突变研究的进展和新兴趋势.
- 识别关键贡献者,有影响力的出版物和该领域的突出研究主题.
- 提供关于艾滋病毒耐药性研究演变的见解,并预测未来的方向.
主要方法:
- 使用CiteSpace软件对3694篇关于药物耐药性突变的出版物进行了图书统计分析.
- 分析了来自Web of Science核心集合的数据.
- 中间的中心性,出版数和爆发值被用作分析标准.
主要成果:
- 对艾滋病毒药物耐药性突变的研究显示,过去十年来,类似波浪的趋势.
- 美国,伦敦大学和Mark A. Wainberg是主要的贡献者.
- 关键的研究领域包括下一代测序,tenofovir alafenamide,儿科耐药性,以及特定药物,如 dolutegravir 和 rilpivirine.
结论:
- 图书统计分析提供了对HIV药物耐药性突变研究领域的视觉概述.
- 这项研究强调了该领域的演变,当前模式和新兴趋势.
- 这些发现为研究人员提供了资源,以促进对艾滋病毒耐药性的理解和管理.
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