一项关于COVID-19和结核病联合感染患者临床概况和结果的描述性研究
Jubert P Benedicto1, Enrick Joshua M Cruz1, Milraam L Quinto1
1Division of Pulmonary Medicine, Department of Medicine, Philippine General Hospital, University of the Philippines Manila.
与单独的COVID-19相比,结核病 (TB) 和COVID-19联合感染导致死亡率显著上升,住院时间更长. 由于症状相似,建议进行双向查.
科学领域:
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
- 临床医学 临床医学
背景情况:
- 结核病 (TB) 控制仍然是一个挑战,对健康有重大影响.
- COVID-19造成了大量的发病率和死亡率,特别是在住院患者中.
- 结核病和COVID-19 (COVID-TB) 的同时感染可能导致严重的结果,当地数据有限.
研究的目的:
- 描述入住第三级医院的COVID-TB患者的人口统计和临床结果.
- 将COVID-TB患者的临床结果与没有结核病的COVID-19患者的临床结果进行比较.
- 分析COVID-TB患者的严重程度,ICU入院,入院时间和死亡率.
主要方法:
- 在接受COVID-19和结核病共感染的患者中进行了一项描述性研究.
- 数据是在2020年3月至2020年9月期间在菲律宾总医院收集的.
- 在COVID-TB患者和一般COVID-19患者之间比较了临床结果.
主要成果:
- 分析了79名COVID-TB患者;70.9%是男性,平均年龄54岁. 大多数患者患有肺结核 (94.9%) 和并发性疾病.
- COVID-TB患者经历了严重/危急的COVID-19疾病 (55.6%),需要氧气 (77%),并有36.7%的住院死亡率.
- 对于COVID-TB (36.7%) 的死亡率明显高于仅仅针对COVID-19 (17.5%). 平均住院时间为21.1天.
结论:
- 与单独的COVID-19相比,COVID-TB与严重程度和死亡率的增加有关.
- 这些发现强调了结核病和COVID-19联合感染的关键影响.
- 由于症状重叠,建议进行双向查,即使在分类时也是如此.
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