基因知识尺度的希腊语和德语翻译,验证和比较
Florian Melchior1, Konrad Beyreuther1, Birgit Teichmann1
1Network Aging Research (NAR), Heidelberg University, Heidelberg, Germany.
Frontiers in genetics
|May 30, 2024
概括
这项研究翻译和验证了遗传学知识尺度,发现现代遗传学和基因组学知识 (KMGG) 问卷是非常有效的. 虽然基因和遗传学的一般知识 (GKGH) 显示出混合的结果,但德国样本显示出对遗传技术的卓越理解.
科学领域:
- 遗传学和基因组学 遗传学和基因组学
- 生物伦理学生物伦理学
- 心理测量 心理测量 心理测量
背景情况:
- 生物科学的进步,包括基因测试和基因编辑 (例如,CRISPR/Cas),需要评估公众理解的工具.
- 目前用于测量公众对遗传学知识的工具有限,因此需要验证的尺度表.
研究的目的:
- 翻译和验证评估公众遗传学知识的尺度,特别是基因和遗传的一般知识 (GKGH),基因与环境相互作用的知识 (KGEI) 和现代遗传学和基因组学知识 (KMGG).
- 评估这些翻译尺度的心理测量特性,包括内部一致性,有效性和可靠性.
主要方法:
- 这是一项横截面研究,涉及567名来自德国和希腊的参与者,他们通过谷歌表单填写了翻译的问卷.
- 心理测量分析包括内部一致性,结构和构造有效性以及重新测试可靠性.
- 研究人员检查了知识分数与人口统计学/经验因素 (性别,教育,宗教信仰,年龄,先前的遗传测试经验) 之间的相关性.
主要成果:
- 现代遗传学和基因组学知识 (KMGG) 调查问卷在所有分析中都显示出出色的心理测量特性.
- 基因和遗传学的一般知识 (GKGH) 显示出良好的再测试和构造有效性,但在内部一致性和项目分析方面存在差异,在德国样本中具有天花板效应.
- 关于基因环境相互作用的知识 (KGEI) 显示了可接受的构造有效性和项目分析,但整体上不那么强大.
- 高等教育水平与对遗传技术的更多知识有显著的相关性.
- 与希腊样本相比,德国样本对遗传技术的理解程度更高.
结论:
- 基因基因基因测试是评估公众对现代遗传学和基因组学知识的可靠和有效工具.
- 由于心理测量方面的局限性,GKGH和KGEI需要进一步改进,或者可能不太适合广泛的公众评估.
- 公众对遗传技术的理解受教育程度的影响,并观察到国家差异.
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