幸存的双鱼Mytilus galloprovincialis的不同恢复模式,基于暴露于球形或纤维状聚乙烯微塑料的转录组概况
Boobal Rangaswamy1, Jinsung An2, Ihn-Sil Kwak3
1Department of Biotechnology, PSG College of Arts & Science, Coimbatore, Tamil Nadu 641014, India.
Heliyon
|May 30, 2024
概括
微塑料 (MPs) 引起细胞应激,并破坏贝的状功能. 虽然球形MPs通过抗氧化基因促进恢复,但纤维MPs导致延迟生存,突出显示了各种生态毒理影响.
科学领域:
- 海洋生物学 海洋生物学
- 生态毒理学 生态毒理学
- 分子生物学分子生物学
背景情况:
- 微塑料 (MP) 是广泛存在的环境污染物.
- 像Mytilus galloprovincialis这样的海洋双动物容易受到MP的摄入.
- 了解MP毒性机制对于生态系统健康至关重要.
研究的目的:
- 为了研究Mytilus galloprovincialis对聚乙烯MPs的转录基因反应.
- 为了比较球形与纤维状MPs对鱼生理学的影响.
- 为了阐明细胞应激和恢复途径.
主要方法:
- 对Mytilus galloprovincialis进行了转录形状分析.
- 贝类暴露在两种聚乙烯微塑料中14天.
- 分析与细胞压力,细胞亡和新陈代谢相关的基因表达模式.
主要成果:
- 国会议员诱导了细胞应激和反应性氧物种 (ROS) 生产.
- 摄入的MPs阻碍了乳毛的运动,并破坏了细胞骨组织.
- 球形MP导致抗亡和抗氧化基因的上调,表明恢复.
- 纤维MPs导致延迟恢复,具有补偿性代谢调节.
结论:
- 贝对不同的微塑料形态表现出不同的分子反应.
- 亡和抗氧化途径是贝对MP毒性的反应的关键.
- 该研究强调了海洋环境中微塑料的生态毒理风险以及需要监管的必要性.
相关概念视频
01:27Bioplastics
Bioplastics derived from microbial processes present a sustainable alternative to conventional petroleum-based plastics. Among these, polyhydroxyalkanoates (PHAs), particularly polyhydroxybutyrates (PHBs), have emerged as prominent candidates due to their biodegradability and biocompatibility. These polymers are synthesized by a variety of bacteria, such as Cupriavidus necator and Pseudomonas putida, which naturally accumulate PHAs as intracellular carbon and energy reserves, especially under...
01:28Microbial Bioremediation of Plastics
Polyethylene terephthalate (PET) is a synthetic polymer widely utilized in the packaging industry, particularly for bottles and containers. Due to its chemical stability and durability, PET accumulates in the environment, contributing significantly to plastic pollution. It comprises repeating units of terephthalic acid and ethylene glycol, resulting in a semi-crystalline structure that is resistant to natural degradation processes.A notable breakthrough in plastic biodegradation came with the...