使用4D流MRI对肺高血压的定量评估:一项回顾性研究
Hirofumi Koike1, Takamasa Nishimura1, Minoru Morikawa1
1Department of Radiology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki University School of Medicine, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Heliyon
|May 30, 2024
概括
四维流动MRI可以量化肺动脉流量参数,以识别肺高血压 (PH). 这种非侵入性成像技术显示出对PH患者监测的前景,为侵入性心脏导管治疗提供了替代方案.
科学领域:
- 心血管成像 - 心血管成像
- 医学物理 医学物理
- 放射学 放射学是一门学科.
背景情况:
- 肺高血压 (PH) 是一种严重的血管疾病,影响心力衰竭患者.
- 目前的诊断依赖于侵入性右侧心脏导管,不适合长期监测.
- 对于准确和可重复的PH评估,需要使用非侵入性方法.
研究的目的:
- 评估4D流磁共振成像 (MRI) 对于肺动脉流量参数的定量评估的实用性.
- 为了确定4D流MRI能否区分PH和没有PH的患者.
- 探索4D流MRI作为监测PH的潜在工具.
主要方法:
- 对97名患者进行了回顾性研究,这些患者根据心声图 (echocardiographic) 的肺动脉静脉压 (PASP) 进行了分类.
- 4D流动MRI被用于定量分析血液流动,速度,反,壁剪应力 (WSS) 和肺动脉中的动能.
- 图像分析是由两个盲目放射科医生独立进行的.
主要成果:
- 在肺动脉干和分支中,在三个患者组 (正常,边界PH,PH) 中观察到WSS的显著差异.
- 动能和平均穿透速度在肺动脉干和右主肺动脉中显示出显著的变化.
- 右主肺动脉的流量也在各组之间存在显著差异.
结论:
- 4D流量MRI有效量化肺动脉流量参数.
- 该技术可以区分患有和没有肺高血压的患者.
- 4D流式MRI显示出作为PH诊断和监测的非侵入性工具的潜力.
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