根据年龄对抗激发药物处方模式的评估在急诊室
1Veterans Affairs Southern Nevada Healthcare System, North Las Vegas.
概括
在年轻人和老年人之间,对急性兴奋管理的处方做法有所不同. 虽然药物选择因年龄而异,但在这个回顾性研究中,安全结果在各组中保持相似.
科学领域:
- 紧急医疗 紧急医疗
- 老年医学 老年医学
- 药理学 药理学是指药理学的学科.
背景情况:
- 急性动是急诊室常见的情况,需要及时管理.
- 二和抗精神病药物是标准的治疗方法,但存在风险,特别是在老年人中.
- 了解特定年龄的处方模式对于安全有效的护理至关重要.
研究的目的:
- 为了比较18-64岁的成年人与65岁及以上的成年人的抗兴奋药物的处方做法.
- 为了确定这些年龄组之间的药物选择和安全结果的差异.
主要方法:
- 对接受哈洛佩里多尔,德罗佩里多尔,洛拉泽巴姆,奥兰扎或齐普拉西的患者的回顾性病理表审查.
- 纳入标准侧重于因激动而接受治疗的患者,不包括戒断综合征.
- 评估的安全结果包括氧和,需要补充氧气,输管,QTc延长和低血压.
主要成果:
- 在年龄组之间观察到抗兴奋药物选择的显著差异 (P = .02).
- 老年人 (≥65岁) 有较高的认知障碍/痴呆率和精神状态改变的诊断.
- 在安全结果或在年龄组之间给予额外的抗兴奋剂量方面没有发现显著差异.
结论:
- 年龄影响抗兴奋药物处方模式在急诊室.
- 兴奋的病因也可能因患者的年龄而异.
- 需要进一步的研究来优化老年人急性兴奋管理.
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