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寒冷和细颗粒物之间的相互作用对西宁死亡风险的影响:在高海拔地区进行的一项案例交叉研究

Zhenxu Ning¹, Shuzhen He², Qiansheng Liu¹

¹Department of Public Health, Faculty of Medicine, Qinghai University, Xining, China.

Frontiers in public health

|May 30, 2024

概括

寒冷和细颗粒物 (PM2.5) 空气污染有协同作用,增加死亡风险,特别是在高海拔地区. 弱势群体如老年人和男性需要有针对性的公共卫生干预措施.

科学领域:

环境健康环境健康
流行病学流行病学
气候变化影响气候变化影响

背景情况:

全球气候变化加剧了寒冷时期和PM2.5空气污染的健康风险.
高海拔地区对这些环境压力因素特别敏感.
了解感冒和PM2.5之间的相互作用对于公共卫生战略至关重要.

研究的目的:

调查寒冷时期,PM2.5暴露和高海拔地区因各种原因的死亡率之间的联系.
评估寒冷时期和PM2.5之间对死亡率的协同作用.
识别与这些暴露相关的脆弱人群和风险因素.

主要方法:

利用了Xining的气象,空气污染 (PM2.5) 和死亡率的时间序列数据.
采用了具有条件后勤回归的时间分层案例交叉设计.
使用因相互作用 (REOI),可归因比例 (AP) 和协同作用指数 (S) 的相对过剩几率来量化相互作用效应.

主要成果:

在感冒,PM2.5和死亡率之间发现了显著的关联,特别是呼吸道疾病和COPD.
寒冷时期和PM2.5对死亡率的协同作用得到证实 (REOI>0,AP>0,S>1).
高达9.56%的非意外死亡被归因于同时暴露;高海拔,男性,老年人和较低教育水平显示敏感性增加.

结论:

暴露于寒冷和PM2.5在高海拔地区构成显著的死亡风险,具有可证明的相互作用效应.
老年人,男性和受教育程度较低的个人被确定为特别脆弱的人群.
减少对寒冷和PM2.5的暴露对于保护敏感地区的公共健康至关重要.

关键词:

空气污染空气污染气候变化气候变化气候变化寒冷的咒语是一个冷的咒语.微细颗粒物质的细颗粒物质的细颗粒物质的细颗粒物质.死亡率死亡率

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