在呼吸补偿点以上的运动期间,外周化学受体对高头的呼吸反应
Aaron J Thompson1, Madeline D Wright1, Leah M Mann1
1Department of Kinesiology, University of Waterloo, Waterloo, Ontario, Canada.
Journal of applied physiology (Bethesda, Md. : 1985)
|May 30, 2024
概括
周围超性化学敏感性 (PHC) 不会随着运动强度超过呼吸补偿点而增加. 运动前的二氧化碳水平,而不是运动本身,影响PHC,这表明运动可能会使这种反应敏感.
科学领域:
- 运动生理学 运动生理学
- 呼吸系统控制 呼吸系统控制
- 心肺功能 心肺功能
背景情况:
- 周围超细胞化学敏感性 (PHC) 对于在运动期间调节通风至关重要.
- 在高强度运动中,特别是呼吸补偿点 (RCP) 以上,理解PHC变化是有限的.
- 已知的呼吸器刺激剂在超RCP强度下发生变化,可能会改变PHC.
研究的目的:
- 调查超RCP运动强度对PHC的影响.
- 为了确定PHC是否在休息和强度运动后的休息之间有所不同.
- 在动态练习过程中探索潮尾PCO2和PHC之间的关系.
主要方法:
- 20名健康受试者接受了最大运动测试,随后进行了休息时的过渡性头过高测试,40% Wmax,85% Wmax,以及运动后的休息.
- 过渡性高头症包括重复呼吸10%的二氧化碳,以评估通风变化.
- 重复测量相关性分析了终潮PCO2和PHC之间的关系.
主要成果:
- 在休息,40%Wmax和85%Wmax运动强度之间,PHC没有显著差异.
- 在运动前休息和运动后休息之间没有观察到PHC的显著差异.
- 在85%Wmax时,终潮PCO2和PHC之间发现了显著的正相关性.
结论:
- 在超RCP运动期间的生理变化不会增加PHC.
- 运动前,运动结束时的PCO2水平调节PHC.
- 运动可能会使PHC变得敏感,无论强度高于RCP.
更多相关视频
相关概念视频
Hyperpnea and Hyperventilation
1.0K
Hyperventilation refers to a higher-than-normal rate and depth of breathing, often associated with anxiety attacks. This excessive breathing surpasses the body's need to expel CO2, leading to a condition known as hypocapnia - an unusually low level of carbon dioxide in the blood. Hypocapnia can constrict cerebral blood vessels, reducing blood flow to the brain, which may result in dizziness or fainting. Early signs include tingling and muscle spasms in the hands and face, caused by falling...
1.0K
Chemical Factors Affecting Respiration Centers
1.1K
Chemical factors such as changing CO2, O2, and H+ levels in arterial blood play a critical role in influencing respiration depth and rates. These variations are detected by chemoreceptors—specialized sensors located in two primary body areas. Central chemoreceptors are found throughout the brain stem, including the ventrolateral medulla, while peripheral chemoreceptors are located in the aortic arch and carotid arteries.
CO2 has a potent influence on respiration and is strictly regulated....
CO2 has a potent influence on respiration and is strictly regulated....
1.1K
Respiratory Regulation of Acid-Base Balance
365
Respiratory compensation is a vital physiological process that stabilizes blood plasma pH by regulating the partial pressure of carbon dioxide (PCO2), a key determinant of pH levels. Most carbon dioxide in the blood dissolves and converts into carbonic acid (H2CO3). It dissociates into hydrogen ions (H+) and bicarbonate ions (HCO3⁻). There is also an inverse relationship between PCO2 and pH.
When carbon dioxide levels increase in the blood, more H+ and HCO3⁻ are...
When carbon dioxide levels increase in the blood, more H+ and HCO3⁻ are...
365
Acute Respiratory Failure-III
174
Hypercapnic respiratory failure, also known as Type 2 or ventilatory respiratory failure, is a severe condition characterized by the body's inability to effectively remove carbon dioxide (CO2) from the bloodstream. It leads to an arterial CO2 pressure (PaCO2) exceeding 45 mmHg and a blood pH above 7.35. This situation indicates that the body's ventilatory demand, or the ventilation needed to maintain normal PaCO2 levels, surpasses its supply or the maximum gas flow achievable without...
174
Compensation Mechanisms
266
The human body employs intricate mechanisms to counteract changes in blood pH, preventing conditions like acidosis (pH < 7.35) and alkalosis (pH > 7.45). These compensatory responses aim to restore normal arterial blood pH by engaging respiratory or renal systems, depending on the source of the imbalance.
Respiratory Compensation
This mechanism addresses metabolic-induced pH imbalances by adjusting breathing rates. Respiratory compensation begins within minutes of detecting a pH...
Respiratory Compensation
This mechanism addresses metabolic-induced pH imbalances by adjusting breathing rates. Respiratory compensation begins within minutes of detecting a pH...
266
Physiological Control of Respiration
2.0K
Introduction
Breathing, a seemingly passive process, is regulated by the respiratory center in the brainstem. This center coordinates the involuntary control of respirations, which means it occurs without conscious effort, ensuring a smooth and uninterrupted pattern.
Regulation of Ventilation
The body maintains ventilation by monitoring levels of carbon dioxide (CO2), oxygen (O2), and hydrogen ion concentration (pH) in the arterial blood. Among these factors, the level of CO2 plays a crucial...
Breathing, a seemingly passive process, is regulated by the respiratory center in the brainstem. This center coordinates the involuntary control of respirations, which means it occurs without conscious effort, ensuring a smooth and uninterrupted pattern.
Regulation of Ventilation
The body maintains ventilation by monitoring levels of carbon dioxide (CO2), oxygen (O2), and hydrogen ion concentration (pH) in the arterial blood. Among these factors, the level of CO2 plays a crucial...
2.0K


