在mRNA疫苗研究中的解码趋势:一项全面的文献计量研究.
Chaobin Zhang1, Yuhang Wang2, Jianding Peng2
1Southwest Eye Hospital, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China.
Human vaccines & immunotherapeutics
|May 30, 2024
概括
使者RNA (mRNA) 疫苗正在彻底改变传染病预防,提供快速发展和适应性. 这项研究绘制了现场地图.
科学领域:
- 疫苗学 疫苗学 疫苗学
- 生物技术是生物技术.
- 免疫学 免疫学 免疫学
背景情况:
- 使者RNA (mRNA) 疫苗已成为对抗传染病的关键工具,其在COVID-19大流行期间的作用就是一个例子.
- 疫苗技术的快速发展,适应新变体的能力和简单性,使得mRNA疫苗技术在全球获得了显著的认可,包括2023年诺贝尔奖.
- 传染病的社会经济影响强调了像mRNA这样的创新疫苗平台的重要性.
研究的目的:
- 对mRNA疫苗研究进行全面的文献分析.
- 绘制mRNA疫苗领域的发展历史,成就和关键参与者的地图.
- 确定目前的mRNA疫苗技术研究热点和未来的优先事项.
主要方法:
- 利用网络科学核心集合 (WoSCC) 数据库对2003年至2023年间发表的5512篇mRNA疫苗论文进行了文献计量分析.
- 采用合作映射,共同引用分析和关键词聚类来分析研究趋势和合作.
- 生成知识地图以可视化国家,机构,作者和期刊的贡献.
主要成果:
- 确定了mRNA疫苗研究中的关键国家,机构,有影响力的作者和主要期刊.
- 强调了塑造该领域的开创性参考.
- 揭示了当前的研究前沿,包括免疫反应,稳定性增强,癌症应用和传染病控制.
结论:
- mRNA疫苗代表了预防传染病的转型性进步.
- 这种文献计量分析为mRNA疫苗的增长轨迹和关键研究领域提供了宝贵的见解.
- 这些发现可以指导未来的研究重点和疫苗开发技术进步.
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