相关实验视频

Updated: Jun 25, 2025

Culturing and Screening the Plant Parasitic Nematode Ditylenchus dipsaci
08:04

Culturing and Screening the Plant Parasitic Nematode Ditylenchus dipsaci

Published on: January 31, 2022

3.4K

迪亚西诺尼古丁杀虫剂的功效和目标表面相互作用

Takehito Terajima1, Chihiro Ayabe1, Yutsuki Matsumoto1

  • 1Department of Chemistry, Faculty of Life Sciences, Tokyo University of Agriculture, Setagaya, Tokyo 156-8502, Japan.

Journal of agricultural and food chemistry
|May 30, 2024
PubMed
概括

研究人员研究了针对昆虫尼古丁乙胆受体 (nAChRs) 的新杀虫剂化合物. 一种新的pyrazinoyl类似物显示出高亲和力和杀虫活性,为控制耐药害虫提供了潜力.

关键词:
乙胺胺的使用方法乙烯基胆结合蛋白是一种结合蛋白.伊米达克洛普里德 (Imidacloprid) 是一种尼古丁是一种尼古丁.尼古丁酸乙胆受体是什么

更多相关视频

Protocols for Testing the Toxicity of Novel Insecticidal Chemistries to Mosquitoes09:32

Protocols for Testing the Toxicity of Novel Insecticidal Chemistries to Mosquitoes

Published on: February 13, 2019

15.6K
Topical Application Bioassay to Quantify Insecticide Toxicity for Mosquitoes and Fruit Flies09:37

Topical Application Bioassay to Quantify Insecticide Toxicity for Mosquitoes and Fruit Flies

Published on: January 19, 2022

5.9K

相关概念视频

Cholinergic Receptors: Nicotinic01:15

Cholinergic Receptors: Nicotinic

Nicotinic receptors are ligand-gated ion channels that are activated by acetylcholine and nicotine. Upon activation, they cause a rapid increase in the permeability of cells to K+, Na+, and Ca2+, followed by depolarization and excitation. They are in the autonomic ganglia, skeletal neuromuscular junction, CNS, and adrenal medulla.
There are two types of nicotinic receptors: neuromuscular (NM/NM/N1) and neuronal (NN/NN/N2). The two families differ based on their location and selectivity to...
2.6K
Dose-Response Relationship: Potency and Efficacy01:22

Dose-Response Relationship: Potency and Efficacy

The potency of a drug is the measure of its ability to produce a biological response and can be compared by looking at the half-maximum effective concentration or EC50 values of different drugs. A lower EC50 value indicates higher potency of the drug. In the dose–response curve of two antihypertensive drugs, candesartan and irbesartan, a significant difference is observed in their EC50 values. A lower EC50 value for candesartan indicates that it is more potent than irbesartan, as it...
4.4K
1° Amines to Diazonium or Aryldiazonium Salts: Diazotization with NaNO2 Mechanism01:37

1° Amines to Diazonium or Aryldiazonium Salts: Diazotization with NaNO2 Mechanism

Nitrous acid is a relatively weak and unstable acid prepared in situ by the reaction of sodium nitrite and cold, dilute hydrochloric acid. In an acidic solution, the nitrous acid undergoes protonation when it loses water to form a nitrosonium ion—an electrophile. Nitrous acid reacts with primary amines to give diazonium salts. The reaction is called diazotization of primary amines.
3.8K
Indirect-Acting Cholinergic Agonists: Pharmacokinetics01:22

Indirect-Acting Cholinergic Agonists: Pharmacokinetics

Indirect-acting cholinergic agonists, or anticholinesterases, enhance the body's cholinergic activity by inhibiting acetylcholine's breakdown. They are categorized as reversible or irreversible agents based on their mechanism of action. They are further classified into short-acting, intermediate-acting, and long-acting agents based on their duration of action.
Reversible agents containing quaternary amines, such as neostigmine and edrophonium, are not easily absorbed orally because they...
963
Indirect-Acting Cholinergic Agonists: Mechanism of Action01:18

Indirect-Acting Cholinergic Agonists: Mechanism of Action

Indirect-acting cholinergic agonists work by interacting with an enzyme called acetylcholinesterase (AChE) in the synaptic cleft. They can be reversible or irreversible inhibitors and have different effects on the enzyme.
Reversible inhibitors like edrophonium bind to a specific part of the enzyme called the anionic catalytic site. They form noncovalent bonds, which means they are not strongly attached to the enzyme. This creates a temporary and less stable enzyme–inhibitor complex,...
1.8K
Indirect-Acting Cholinergic Agonists: Chemistry and Structure-Activity Relationship01:29

Indirect-Acting Cholinergic Agonists: Chemistry and Structure-Activity Relationship

Indirect-acting cholinergic agonists are agents that interact with the acetylcholinesterase enzyme in the synaptic cleft, preventing the breakdown of acetylcholine into choline and acetate. Consequently, the concentration of acetylcholine in the synaptic cleft increases. These agonists can be classified into reversible and irreversible inhibitors based on their duration of action.
Reversible inhibitors display short to medium durations of action. Short-acting agents include simple alcohols with...
554