Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

2D NMR: Heteronuclear Single-Quantum Correlation Spectroscopy (HSQC)01:19

2D NMR: Heteronuclear Single-Quantum Correlation Spectroscopy (HSQC)

685
Heteronuclear single-quantum correlation spectroscopy (HSQC) is a 2D NMR technique that reveals one-bond correlations between hydrogen and a heteronucleus. The HSQC experiment is similar to the heteronuclear correlation experiment (HETCOR) but is more sensitive. In the HSQC spectrum, the proton chemical shift is plotted on the horizontal F2 axis, while the 13C chemical shift is plotted on the vertical F1 axis. The corresponding proton and 13C spectra are also shown. The HSQC contour plot does...
685
2D NMR: Overview of Heteronuclear Correlation Techniques01:18

2D NMR: Overview of Heteronuclear Correlation Techniques

171
Heteronuclear correlation spectroscopy is an analytical technique that investigates the coupling between different types of nuclei, often a proton and an X-nucleus, such as carbon-13 or nitrogen-15. This method is commonly used in nuclear magnetic resonance (NMR) spectroscopy to gain insights into complex chemical compounds' structural and compositional aspects. A typical heteronuclear correlation spectrum displays X-nucleus chemical shifts on one axis and a proton spectrum on the other...
171

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

CRISPR-mediated engineering of bovine satellite cells for Alpha-Gal Syndrome-compatible cultivated meat.

bioRxiv : the preprint server for biology·2026
Same author

Stress-induced loss of CTCF reveals an alternative, promoter-based mode of cohesin looping.

bioRxiv : the preprint server for biology·2026
Same author

Deubiquitinases as prognostic biomarker and potential drug target for gynecological cancers.

International journal of clinical oncology·2025
Same author

Response splicing quantitative trait loci in primary human chondrocytes identify putative osteoarthritis risk genes.

Nature communications·2025
Same author

Why we organized 'Stand Up For Science'.

Nature human behaviour·2025
Same author

Biomolecular condensation of human IDRs initiates endogenous transcription via intrachromosomal looping or high-density promoter localization.

Nucleic acids research·2025
Same journal

Cross-Domain Transfer Learning from Peptides to Metabolites Using a Multi-Property Fine-Tuned LLM.

Bioinformatics (Oxford, England)·2026
Same journal

Biomedical Concept Recognition with Error-aware Negative-enhanced Ranking Framework.

Bioinformatics (Oxford, England)·2026
Same journal

TEDLH: Domain HMMs for sensitive detection of remote homologues.

Bioinformatics (Oxford, England)·2026
Same journal

PLNFGL: Joint Estimation of Multi-Condition Gene Networks from Single-cell RNA-seq Data.

Bioinformatics (Oxford, England)·2026
Same journal

MCFST: Spatial domain identification method based on multi-view graph convolutional network and graph fusion network.

Bioinformatics (Oxford, England)·2026
Same journal

SpaBiT: Enhancing Spatial Transcriptomics Resolution via Bidirectional Attention Transformers.

Bioinformatics (Oxford, England)·2026
查看所有相关文章

相关实验视频

Updated: Jun 25, 2025

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.
22:27

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.

Published on: May 6, 2010

408.9K

航海员:探索Hi-Css的时间

Eric S Davis1,2, Sarah M Parker1, Nicole E Kramer1

  • 1Curriculum in Bioinformatics and Computational Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, United States.

Bioinformatics (Oxford, England)
|May 30, 2024
PubMed
概括
此摘要是机器生成的。

马里纳是一个新的R/生物导体工具,可以高效地处理大型Hi-C数据集,用于3D染色体结构分析. 它简化了提取,聚合和绘制基因组联系数据,帮助对基因表达和疾病的研究.

更多相关视频

Hand Controlled Manipulation of Single Molecules via a Scanning Probe Microscope with a 3D Virtual Reality Interface
11:00

Hand Controlled Manipulation of Single Molecules via a Scanning Probe Microscope with a 3D Virtual Reality Interface

Published on: October 2, 2016

9.0K
Capturing Chromosome Conformation Across Length Scales
10:15

Capturing Chromosome Conformation Across Length Scales

Published on: January 20, 2023

3.4K

相关实验视频

Last Updated: Jun 25, 2025

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.
22:27

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.

Published on: May 6, 2010

408.9K
Hand Controlled Manipulation of Single Molecules via a Scanning Probe Microscope with a 3D Virtual Reality Interface
11:00

Hand Controlled Manipulation of Single Molecules via a Scanning Probe Microscope with a 3D Virtual Reality Interface

Published on: October 2, 2016

9.0K
Capturing Chromosome Conformation Across Length Scales
10:15

Capturing Chromosome Conformation Across Length Scales

Published on: January 20, 2023

3.4K

科学领域:

  • 基因组学就是基因组学.
  • 计算生物学 计算生物学
  • 分子生物学分子生物学

背景情况:

  • 三维染色体结构对于基因调节至关重要.
  • 染色体结构的异常与发育障碍和疾病有关.
  • 高通量染色体构造捕获 (Hi-C) 技术产生大而复杂的数据集.

研究的目的:

  • 介绍一个新的软件工具Mariner,用于分析Hi-C数据.
  • 为处理大型Hi-C矩阵提供快速和内存高效的解决方案.
  • 为了方便提取,3D染色质接触数据的提取,聚合和可视化.

主要方法:

  • 马里纳使用并行和块处理方法来实现高效的数据处理.
  • 该工具为定制分析工作流提供模块化功能.
  • 集成的功能可以在R/生物导体环境中进行共同的Hi-C分析.

主要成果:

  • 马里纳显著加快了Hi-C联系数据的提取和聚合.
  • 该软件有效地处理大型Hi-C矩阵,减少计算负担.
  • 与生物导体的无集成允许进行全面的数据分析和可视化.

结论:

  • 马里纳为3D染色体结构分析提供了强大且易于使用的解决方案.
  • 该工具提高了Hi-C数据解释的可访问性和效率.
  • 马里纳支持高级定制,同时为标准分析提供简单的选项.