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Updated: Jun 25, 2025

In Vivo Modeling of the Morbid Human Genome using Danio rerio
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In Vivo Modeling of the Morbid Human Genome using Danio rerio

Published on: August 24, 2013

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GTExome:在人类基因组中建模常见表达的误解突变

Jill Hoffman1, Henry Tan2, Clara Sandoval-Cooper2

  • 1Computational Bioscience, University of Colorado Anschutz Medical Campus, Aurora, CO, United States of America.

PloS one
|May 30, 2024
PubMed
概括

GTExome是一个新的网络工具,使用组织特定表达数据对人类蛋白质的误解突变进行建模. 该工具有助于理解突变的影响,并促进蛋白相互作用研究.

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相关概念视频

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Mismatch Repair

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Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
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