描述:一个总体审查
Nuša Japelj1, Nejc Horvat1, Lea Knez1,2
11University of Ljubljana Faculty of Pharmacy, Department of Social Pharmacy 1000 Ljubljana, Slovenia.
Acta pharmaceutica (Zagreb, Croatia)
|May 30, 2024
概括
降低处方干预措施有效减少不合适的药物,并改善患者的治疗结果. 然而,药物停用需要仔细监测,以防止不良戒断事件,强调患者的安全性,在减缓的研究.
科学领域:
- 药理学和老年病学 药理学和老年病学
- 证据综合和卫生服务研究研究
背景情况:
- 降低处方包括减少或停止可能不再有益或可能造成伤害的药物.
- 系统性审查对于综合描述干预和结果的证据至关重要.
研究的目的:
- 进行对抑郁症研究的系统性审查的总体审查.
- 分析干预的特征,人口,药物,和设置在抑郁症研究.
- 呈现临床和人文成果,障碍,促进者和抑郁症的工具.
主要方法:
- 在Medline数据库中搜索到到2022年4月发表的关于抑郁症的系统评论和元分析.
- 包括有计划和监督下药的审查;不包括那些没有.
- 根据研究重点 (结果,障碍,工具) 分析了94项系统性审查 (23项元分析).
主要成果:
- 大多数审查 (74%) 集中在临床或人文成果,而较少的处理态度 (18%) 或工具 (8.5%).
- 处方干预试验显示可行性,并减少了不合适的药物.
- 药物戒断试验表明药物戒断不良事件的频率更高,需要谨慎.
结论:
- 处方干预是可行的,可以减少不适当的药物使用.
- 综合药物优化干预措施显示出减少住院治疗,跌倒和死亡率的潜力.
- 在药物停用期间,患者安全和仔细监测至关重要,以减轻戒药风险.
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