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饮食中较高的活微生物摄入量与较低的肉症风险有关
Kemin Yan1, Xiaoyi Ma1, Chen Li1
1Department of Geriatrics, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China; Department of Private Medical Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Clinical nutrition (Edinburgh, Scotland)
|May 30, 2024
概括
饮食中活微生物的摄入量较高与减少患上肉症的风险有关,这种疾病的特征是肌肉损失. 这一发现表明益生菌在维持肌肉健康方面可能发挥作用.
科学领域:
- 老年学是指老年学的学科.
- 营养科学 营养科学
- 肌肉生理学 肌肉生理学
背景情况:
- 萨科佩尼亚是一种与年龄相关的严重疾病,其特点是骨肌肉质量和功能逐渐丧失.
- 饮食因素,包括活微生物 (益生菌),越来越多地被认为对健康结果的潜在影响.
- 了解饮食中活微生物消费与肉症之间的关系对于制定预防策略至关重要.
研究的目的:
- 为了研究饮食中活微生物摄入量与肉类的患病率之间的关联.
- 根据人口统计和健康因素,探索这种关联中的潜在差异.
主要方法:
- 分析了国家健康和营养检查调查 (NHANES) 的5368名参与者的数据.
- 活微生物的饮食摄入量通过自我报告问卷进行评估,并分为低,中,高消费组.
- 根据国家卫生研究院 (NIH) 的定义,使用尾骨肌肉质量和体重指数来诊断萨科佩尼亚.
- 进行多变量回归和分层分析以调整混变量.
主要成果:
- 饮食中高摄入活微生物的个体与摄入量低的人相比,肉症的患病率明显较低 (调整后OR,0.63;95% CI,0.44-0.89).
- 在增加饮食中活微生物摄入量和降低肉症患病率之间观察到一个显著的趋势 (p < 0.05).
- 亚组分析表明,糖尿病状况与饮食中的活微生物对萨尔科佩尼亚风险的影响之间存在潜在的相互作用 (相互作用的p = 0.094).
结论:
- 饮食中活微生物的消费量较高,与低 Sarcopenia 的风险有关.
- 这些发现凸显了益生菌在减轻与年龄相关的肌肉损失方面的潜在作用.
- 需要进一步的研究,特别是干预研究,以证实这些关联并探索机制.
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