在孕期糖尿病和与胎儿胰腺的关联中脏动脉多普勒波形:一项前性病例对照研究
Hakan Golbasi1,2, Burak Bayraktar3, Ceren Golbasi4
1Division of Perinatology, Department of Obstetrics and Gynecology, Bakircay University Cigli Education and Research Hospital, Izmir, Turkey.
Fetal diagnosis and therapy
|May 30, 2024
概括
妊娠期糖尿病 (GDM) 的孕妇表现出更大的胎儿胰腺大小和改变的回声性. 脏动脉 (SA) 多普勒波形表明GDM组的血管阻力增加.
科学领域:
- 产科和妇科 产科和妇科
- 胎儿医学 胎儿医学
- 内分泌学 在内分泌学.
背景情况:
- 孕期糖尿病 (GDM) 影响胎儿发育.
- 评估胎儿器官发育在高风险怀孕中至关重要.
- 胎儿胰腺和动脉参数是GDM影响的潜在指标.
研究的目的:
- 为了评估胎儿胰腺大小和发声性在怀孕妇女与GDM.
- 为了评估脏动脉 (SA) 多普勒波形在胎儿的母亲与GDM.
- 为了将胎儿胰腺特征与GDM中的SA多普勒发现相关联.
主要方法:
- 对124名孕妇进行前性病例控制研究 (62名GDM,62名对照).
- 测量胎儿胰腺周长和回声性.
- 分析了动脉和动脉 (SA) 多普勒指数 (S/D,PI,PSV,PG).
主要成果:
- 胎儿胰腺周长和回声性在GDM组显著更高 (p<0.001).
- 在GDM组中,SA多普勒显示S/D和PI显著更高 (p<0.001,p=0.001).
- 胰腺周长和回声性与SA多普勒参数正相关,表明血管抵抗增加.
结论:
- 胎儿胰腺大小和回声性在GDM怀孕中显著增加.
- 升高的SA多普勒S/D和PI表明,患有GDM的母亲胎儿的血管阻力增加.
- 这些发现突出了监测GDM对胎儿发育影响的潜在超声波标志物.
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