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简要 解决 无法解释的事件 症状 经常导致不适当的胃肠道诊断和治疗
Daniel R Duncan1, Clare Golden1, Amanda S Growdon2
1Aerodigestive Center, Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA.
The Journal of pediatrics
|May 30, 2024
概括
呈现症状的婴儿短暂解决的不明原因事件 (BRUE) 影响诊断测试和胃食道逆流性疾病 (GERD) 诊断,但是不可靠的诊断口腔喉乱. 与症状相关的GERD诊断,增加了抑制酸性药物的使用.
科学领域:
- 儿科 儿科 儿科
- 胃肠病学 胃肠病学
- 神经学 神经学
背景情况:
- 短暂解决的不明原因事件 (BRUE) 是婴儿常见的表现.
- 口腔喉乱和胃食道逆流性疾病 (GERD) 是潜在的潜在原因.
- 在诊断BRUE婴儿这些疾病时表现出症状的作用尚不清楚.
研究的目的:
- 在 BRUE 婴儿中调查表现出症状和口腔喉功能障碍和 GERD 诊断之间的关联.
- 为了检查表现症状,诊断测试 (VFSS) 和酸抑制药物使用之间的关系.
主要方法:
- 对157名患有BRUE的婴儿进行前性队列研究.
- 对呈现症状,视频光学吞研究 (VFSS) 结果和GERD诊断的审查.
- 家长调查以确定酸性抑制药物的使用.
- 逻辑回归模型用于评估关联.
主要成果:
- 呈现症状与执行VFSS的决定有关,但与异常VFSS结果无关.
- 42%的婴儿接受了GERD诊断,33%的婴儿接受了酸性抑制治疗.
- 呈现症状和GERD诊断与使用酸性抑制剂的增加有关 (aOR 2.3).
结论:
- 呈现症状在BRUE中指导VFSS决策,但不足以诊断口腔喉乱.
- 症状可能导致GERD诊断,这与更高的酸性抑制药物使用率有关.
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