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Updated: Jun 25, 2025

Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells
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Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells

Published on: April 26, 2017

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ACLY 替代拼接与癌症表型相关.

Julianna G Supplee1, Hayley C Affronti2, Richard Duan2

  • 1Department of Cancer Biology, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

The Journal of biological chemistry
|May 30, 2024
PubMed
概括

ATP-酸酶 (ACLY) 拼接产生了两种异构体,但功能上的差异仍然不清楚. 尽管在癌症中发生了变化的拼接,但两种异型都不会影响细胞代谢,稳定性或瘤生长,这表明其在癌症中的作用需要进一步调查.

关键词:
酸酸酸酶的ATP-酸.另一个替代拼接方法.癌症 癌症 癌症 癌症表皮分离调节蛋白 1 1异构体的异构体形式代谢过程中的代谢.在TCGA中,TCGA就是TCGA.

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