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Updated: Jun 25, 2025

Murine Colitis Modeling using Dextran Sulfate Sodium DSS
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陶鲁二氧化醇酸通过调节肠道屏障功能障碍和微生物组调节障碍来逆转硫酸德克斯在小鼠中诱导的大肠炎

Longbiao Luo1, Yi Zhao1, Guangji Zhang1

  • 1School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, China (L.L., S.D., Y.X., H.S., M.Z., X.L., S.W., W.J.); Macau Centre for Research and Development in Chinese Medicine, State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China (L.L., H.L.); Department of Pharmacy, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China (Y.Z.); School of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, China (G.Z.); and Shaanxi Engineering Research Center of Cardiovascular Drugs Screening and Analysis, Xi'an, China (S.D., Y.X., H.S., M.Z., X.L., S.W., W.J.).

The Journal of pharmacology and experimental therapeutics
|May 30, 2024
PubMed
概括

塔乌尔苏氧胆酸 (TUDCA) 在性结肠炎 (UC) 方面表现有前途. 这项研究发现,TUDCA减少了炎症,保护了肠道屏障,并在患有大肠炎的小鼠中平衡了肠道微生物群.

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