在免疫相关不良事件的临床管理中使用人工智能聊天机器人
Hannah Burnette1, Aliyah Pabani2, Mitchell S von Itzstein3
1Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Journal for immunotherapy of cancer
|May 30, 2024
概括
人工智能聊天机器人提供有关癌症免疫疗法的免疫相关不良事件 (irAEs) 的准确和完整信息,尽管指南目前仍然是黄金标准.
科学领域:
- 在瘤学瘤学.
- 人工智能的人工智能
- 医疗信息学 医疗信息学
背景情况:
- 人工智能 (AI) 聊天机器人越来越多地用于医疗信息.
- 人工智能产生的医疗信息的准确性和完整性,特别是癌症免疫疗法的免疫相关不良事件 (irAEs),需要进行评估.
研究的目的:
- 评估AI聊天机器人的准确性和完整性,以回答有关免疫相关不良事件 (irAEs) 的问题.
- 为了比较不同AI聊天机器人在提供irAEs信息方面的表现.
主要方法:
- 开发了50个问题和20个患者场景,涉及10个irAE类别.
- 查询了两个AI聊天机器人 (ChatGPT和Bard) 的答案.
- 专家们在利克特等级 (1-4) 上对人工智能生成的答案的准确性和完整性进行了评分.
主要成果:
- 这两种人工智能聊天机器人都表现出高精度 (ChatGPT: 3.87,Bard: 3.5) 和完整性 (ChatGPT: 3.83,Bard: 3.46).
- 不准确或不完整的答案很少见,特别是对于ChatGPT (0.75%).
- 患者场景也获得了准确性 (3.725) 和完整性 (3.61) 的高平均得分.
结论:
- 人工智能聊天机器人在很大程度上提供了关于irAEs的准确和完整信息.
- 有意义的"幻觉"或非常不准确的信息是不常见的.
- 虽然AI正在改善,但当前的临床指南仍然是irAE管理的最终来源.
更多相关视频
06:08Assessment of Chimeric Antigen Receptor T Cell-Associated Toxicities Using an Acute Lymphoblastic Leukemia Patient-Derived Xenograft Mouse Model
Published on: February 10, 2023
1.3K
07:46Microfluidic Co-Culture Models for Dissecting the Immune Response in in vitro Tumor Microenvironments
Published on: April 30, 2021
4.7K
相关概念视频
01:27Tumor Immunotherapy
514
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
514
01:19Pharmacovigilance
825
Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
825
01:27Allergic Drug Reactions
833
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
833
01:29Issues And Trends In Healthcare Delivery System
5.6K
The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
5.6K
01:17Drugs Used in Lower Respiratory Disorders: Overview
420
Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
420
01:40Cell-mediated Immune Responses
68.1K
Overview
68.1K