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Zhengqiu Zhu1, Lingshan Chen2, Bixiao Shen1
1Department of Ultrasound, Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing, China.
超快脉冲波速度 (ufPWV) 测量显示,心动脉硬与健康个体的心血管风险有关. 这些ufPWV指数可能有助于对年轻人群的风险进行分层.
科学领域:
- 心血管科学 心血管科学
- 医疗成像医学成像
- 生物医学工程 生物医学工程
背景情况:
- 心血管风险分层对于预防医学至关重要.
- 冠状动脉硬化是心血管疾病的早期指标.
- 弗雷明汉风险评分 (FRS) 是估计心血管风险的广泛使用工具.
研究的目的:
- 通过FRS估计的心血管风险和通过超快脉冲波速度 (ufPWV) 测量的动脉硬化之间的关联.
- 评估ufPWV在看似健康的个体中风险分层的有用性.
主要方法:
- 1034名健康参与者接受了ufPWV测量.
- 使用PWV-BS和PWV-ES评估了心硬化.
- 根据FRS,参与者被分为低,中等和高心血管风险组.
- 进行多变量逻辑回归分析以评估关联.
主要成果:
- 冠状动脉硬化 (PWV-BS和PWV-ES) 在FRS风险类别之间存在显著差异.
- 即使在低风险的FRS子类别中,PWV-ES也显示出显著的差异.
- 增加的PWV-BS和PWV-ES独立地与低风险组和中等风险组中的FRS类别相关.
结论:
- ufPWV对动脉硬化的体内成像是独立地与FRS类别联系在一起的.
- ufPWV指数可能有助于在看似健康的年轻人中对心血管风险进行分层.
- ufPWV为早期检测和风险评估提供了一个有前途的工具.
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