糖尿病特异配方对中风非糖尿病住院患者的影响:一项随机对照试验
Juan J López-Gómez1,2,3, Esther Delgado García4,5,6, David Primo-Martín4,5
1Servicio de Endocrinología y Nutrición, Hospital Clínico Universitario de Valladolid, Valladolid, Spain. jjlopez161282@hotmail.com.
Nutrition & diabetes
|May 30, 2024
概括
针对糖尿病的肠道营养配方显著降低了急性中风患者的高血糖风险. 这种专用配方还改善了口服养的恢复率,有助于患者的康复.
科学领域:
- 临床营养学 临床营养学
- 神经学 神经学
- 代谢障碍 代谢障碍 代谢障碍
背景情况:
- 急性中风患者的高血糖与更糟糕的结果和神经恢复的减少有关.
- 肠道营养 (EN) 对于中风后无法口服食用的患者至关重要.
- 评估专用配方是优化治疗中风患者的关键,这些患者的葡萄糖代谢发生变化.
研究的目的:
- 评估糖尿病特异性肠道营养配方对非糖尿病急性中风患者血糖控制的影响.
- 评估这种专用配方对并发病和死亡率的影响.
- 为了确定配方是否改善神经恢复和口服养恢复.
主要方法:
- 一项前性随机对照试验,涉及52名非糖尿病急性中风患者,需要鼻胃管养.
- 患者被随机分配,接受标准的同热量同蛋白配方 (对照) 或糖尿病特异的配方 (实验).
- 测量的主要结果包括高血糖发生率,HbA1c,胰岛素使用,口服途径恢复,停留时间和30天死亡率.
主要成果:
- 实验组 (糖尿病特异配方) 在第5天显示高血糖的发生率明显降低 (35%vs65%).
- 接受糖尿病特异性配方的患者口服途径恢复率更高 (44%与18.5%相比).
- 两组之间没有观察到停留时间或30天死亡率的显著差异.
结论:
- 一种针对糖尿病的肠道配方有效地降低了非糖尿病急性中风患者高血糖的风险.
- 这种专用配方增加了恢复口服养能力的可能性.
- 这些发现支持在中风管理中使用有针对性的肠道营养策略.
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