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Updated: Jun 25, 2025

High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents HPHC
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Published on: May 10, 2016

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在I期临床试验中延迟毒性的分量累积无校准几率 (f-aCFO) 设计

Jialu Fang1, Guosheng Yin1

  • 1Department of Statistics and Actuarial Science, The University of Hong Kong, Hong Kong, China.

Statistics in medicine
|May 31, 2024
PubMed
概括

新的无校准累积赔率 (aCFO) 设计通过使用所有剂量信息来提高第一阶段试验的效率. 增强版本的TITE-aCFO和f-aCFO有效地管理晚发性毒性,提供强大的和用户友好的试验行为.

关键词:
贝叶斯设计是贝叶斯的设计.剂量确定试验试验.晚期发生的毒性.赔率比率 赔率比率 的比率.第一个阶段的试验试验.

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