口服益生菌对尾切除术后成年患者炎症和肠功能的影响:随机对照试验
Ke Lan1, Ke-Rui Zeng1, Fu-Rui Zhong1
1Department of General Surgery, Zigong Fourth People's Hospital, Zigong 643000, Sichuan Province, China.
World journal of gastrointestinal surgery
|May 31, 2024
概括
手术后的益生菌在尾切除术后显著降低了诸如C反应性蛋白 (CRP) 和公素 (PCT) 等炎症标志物. 这种干预措施也加速了恢复,因为它缩短了第一次浮气的时间.
科学领域:
- 胃肠病学 胃肠病学
- 微生物学 微生物学
- 术后恢复 术后恢复
背景情况:
- 尾切除术是一种急性腹部手术,通常会导致严重的炎症.
- 口服益生菌正在探索增强术后恢复.
- 对尾切除术后益生菌的前性研究是有限的.
研究的目的:
- 评估术后益生菌对炎症反应的影响.
- 评估尾切除术后肠道功能的恢复情况.
- 为了研究尾切除术患者*Bacillus licheniformis*的疗效.
主要方法:
- 一项前性随机试验,涉及60名接受紧急尾切除术的患者.
- 患者被分为对照组和益生菌组,分别接受*Bacillus licheniformis*治疗5天.
- 监测和分析了炎症标志物和术后情况.
主要成果:
- 益生菌组在手术后的第二天和第五天显示出显著较低的C-反应蛋白 (CRP),白蛋白6和白素 (PCT) 水平.
- 接受益生菌治疗的患者经历了较短的时间到第一次浮.
- 在益生菌组的便中观察到更高的格拉姆阴性细菌百分比.
结论:
- 手术后的口服益生菌可以调节肠道微生物群的组成.
- 益生菌似乎有利于尾切除术后的早期炎症反应恢复.
- 这种干预措施显示了增强尾切除术后患者整体康复的潜力.
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