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Lunla Udomwech¹, Rini Sulastiwaty², Doungkamol Siriarchawawat³

¹Department of Ophthalmology, School of Medicine, Walailak University, Thasala, Nakhonsithammarat, Thailand.

|May 31, 2024

概括

偏头痛患者表现出改变的视网膜层厚度,增加了内核层 (INL) 和减少了脑细胞层 (GCL) 和视网膜神经纤维层 (RNFL) 在头痛侧眼睛中. 这些变化与偏头痛的严重程度相关.

科学领域:

眼科医生眼科眼科
神经学神经学
神经科学是一个神经科学.

背景情况:

偏头痛涉及三角血管系统的激活,释放神经递质,可以导致异常血管收缩.
眼睛系统的影响,包括潜在的视网膜损伤,与偏头痛引起的血管收缩有关.
了解偏头痛中的视网膜层差异对于诊断和管理潜在的眼部并发症至关重要.

研究的目的:

调查偏头痛患者和健康对照人群之间的视网膜层厚度差异.
评估特定的视网膜层,包括周和黄斑视网膜神经纤维层 (pRNFL和mRNFL),状细胞层 (GCL),内状层 (IPL) 和内核层 (INL).

主要方法:

采用了一种病例控制研究设计.
招募了38名偏头痛患者和38名年龄和性别匹配的健康对照.
使用光学连贯断层扫描 (OCT) 来测量特定视网膜层的厚度.

主要成果:

偏头痛患者与对照人群相比,表现出更厚的上部外部内核层 (INL).
在偏头痛患者头痛侧眼睛的外细胞层 (GCL) 和上外黄斑视网膜神经纤维层 (mRNFL) 中观察到较小的厚度.
头痛侧眼中的INL厚度与偏头痛残疾分数负相关.

结论:

偏头痛中INL厚度增加可能与炎症过程有关.
在严重的偏头痛病例中,渐进的视网膜神经元损失可能会导致与不那么严重的病例相比,INL变薄.
这项研究是首次报告了偏头痛患者头痛侧眼睛中GCL和mRNFL的稀释.

关键词:

团结体细胞层是一个团结细胞层.内核层是内部的核层.偏头痛是一种偏头痛.光学连贯性断层扫描仪视网膜神经纤维层是一种神经纤维层.厚度厚度厚度厚度

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