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Updated: Jul 17, 2026

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一项关于IDO/TDO抑制剂的活性和选择性的理论研究

Baerlike Wujieti1, Xinping Feng1, Erxia Liu1

  • 1School of Chemical Sciences, University of Chinese Academy of Sciences, No. 19A, YuQuan Road, Beijing 100049, China. cuiwei@ucas.ac.cn.

Physical chemistry chemical physics : PCCP
|May 31, 2024
PubMed
概括

印度醇胺2,3-二氧化酶1 (IDO) 和二氧化酶 (TDO) 是瘤免疫治疗的关键标. 这项研究阐明了它们对选择性抑制剂设计的结构性要求,这对于增强抗瘤免疫反应和克服耐药性至关重要.

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