阻塞性睡眠呼吸暂停综合征对嗅觉和味觉能力的影响
Eleonora M C Trecca1,2, Pier Gerardo Marano1, Ferruccio Madaro3
1Department of Otorhinolaryngology, University Hospital of Foggia, Head and Neck Surgery, Foggia, Italy.
Chemical senses
|May 31, 2024
概括
患有阻塞性睡眠呼吸暂停综合征 (OSAS) 的患者经历了明显减少的嗅觉和味觉感知. 这项研究发现,与对照组相比,OSAS患者的感觉功能受损,突出显示了与嗜睡的潜在联系.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 睡眠医学 睡眠医学
- 神经科学是一个神经科学.
背景情况:
- 有限的研究存在于阻塞性睡眠呼吸暂停综合征 (OSAS) 中的嗅觉和味觉功能.
- 现有的文献缺乏对OSAS患者的全面口味评估.
- 了解OSAS感官缺陷对于全面的患者评估至关重要.
研究的目的:
- 为了评估被诊断患有OSAS的患者的嗅觉和味觉感知.
- 调查OSAS严重程度与感官功能之间的关系.
- 探索嗅觉/味觉得分和嗜睡度量表之间的相关性.
主要方法:
- 该研究包括85名OSAS患者和81名对照患者,通过历史记录,鼻内镜和问卷进行评估.
- OSAS诊断通过多睡眠学证实;鼻空气流量通过鼻腔计量测量.
- 嗅觉功能通过嗅探棒测试 (TDI分数) 进行评估;味觉功能通过子组中的味道带进行评估.
主要成果:
- 在OSAS患者中,TDI平均得分 (31 ± 5.6) 与对照组 (35 ± 4.6) 相比显著降低 (P < 0.001).
- 与对照组 (12.6 ± 3.2) 相比,OSAS患者的味觉得分也显著降低 (7 ± 3.0) (P < 0.001).
- 没有发现TDI/味道得分与呼吸暂停指数 (AHI) 之间有显著的相关性;在TDI和爱普沃思嗜睡量表之间观察到的相关性很弱.
结论:
- 患有OSAS的患者表现出明显受损的嗅觉和味觉感知.
- OSAS (AHI) 的严重程度与感觉障碍的程度没有相关性.
- 需要进一步的研究来阐明OSAS中这些感官缺陷的潜在病理生理学.
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