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益生菌,益生菌和协生菌对伤口感染的影响:系统性审查
Marzie Mahdizade Ari1, Soheila Shahroodian1, Roghayeh Afifirad2
1Department of Microbiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Current pharmaceutical biotechnology
|May 31, 2024
概括
口服益生菌在改善外科创伤感染愈合方面表现有前途. 它们减少了抗生素的使用和没有严重副作用的住院时间,有利于各种手术程序.
科学领域:
- 微生物学 微生物学
- 免疫学 免疫学 免疫学
- 手术科学 手术科学
背景情况:
- 手术部位感染在患者康复过程中带来了重大挑战.
- 口服益生菌疗法是管理伤口感染的新兴策略.
研究的目的:
- 系统地审查有关口服益生菌的证据,以治疗受感染的外科创伤.
- 评估益生菌对康复指标和患者结果的影响.
主要方法:
- 在主要数据库 (2010-2022) 中进行全面的文献搜索.
- 对2625篇文章进行选,其中22篇文章根据纳入标准被选中进行审查.
主要成果:
- 益生菌显著减少了抗生素的持续时间和在手术伤口感染中住院的时间.
- 在各种类型的手术中观察到的积极影响,包括腹部,结直肠和整形手术.
- 在口服益生菌的使用后,没有报告严重的不良事件.
结论:
- 口服益生菌有助于防止病原体生长并保持伤口无菌.
- 益生菌通过招募M2巨细胞和增强细胞活动来调节免疫反应.
- 它们有效地减少了细菌转移,并抑制了促进入侵的介质.
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