确定患有同时存在的益生菌瘤和精神症状的患者的理想管理:系统性审查
Awais Paracha1, Umar Durrani1, Satvik Vasireddy2
1School of Medicine, Saint Louis University, Saint Louis, MO.
Journal of psychiatric practice
|May 31, 2024
概括
管理乳瘤和精神疾病需要仔细调整治疗. 优先考虑某些抗精神病药物和调整多巴胺激动剂可以改善症状,最后手段是手术.
科学领域:
- 内分泌学 在内分泌学.
- 神经精神病学是一种神经精神病学.
背景情况:
- 益生菌瘤由于过多的益生菌因而引起症状.
- 多巴胺激动剂 (DAs) 治疗益生菌瘤,但可能导致精神病副作用.
- 用于治疗精神疾病的多巴胺抗剂可以加剧高血.
研究的目的:
- 为了确定有效的治疗策略,为患者与共存的前乳腺瘤和精神症状.
- 为了应对治疗一种疾病而不加剧另一种疾病的挑战.
主要方法:
- 对PubMed文献 (1960-2023) 的系统综述.
- 包括病例报告,病例系列和两种病症患者的队列研究.
- 通过脑成像,益生素水平和精神病史进行验证.
主要成果:
- 分析了涉及42名参与者的23份报告.
- 64%的患者表现出前素和精神症状的改善.
- 治疗涉及改变抗精神病药物/多巴胺抗剂或中止DA;手术/辐射是最后一线.
结论:
- 优先考虑特定的抗精神病药物 (阿里皮普拉,奥兰沙平,齐普拉西,克洛沙平) 而不是其他.
- 考虑定期停止多巴胺激动剂治疗.
- 如果药物治疗失败,可能需要手术或放射治疗.
- 建议以患者为中心的方法是由于可变的反应.
相关概念视频
01:26Psychosis: Goals of Pharmacotherapy
123
Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
123
01:28Psychosis and Antipsychotic Drugs: Overview
235
The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic...
235
01:24Mania and Antimanic Drugs: Overview
168
Mania, a psychological condition characterized by elevated mood, increased energy, and reduced sleep need, is part of the bipolar disorder cycle. The exact cause of mania isn't entirely known, but it is thought to be a combination of genetic, environmental, and neurological factors. Bipolar disorder involves alternating manic and depressive episodes. Mood stabilizers like lithium, antipsychotics, and anticonvulsants help manage these episodes. Lithium carbonate is particularly effective as...
168
01:28Drug Therapy
42
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Antianxiety Medications
42
01:24Parkinson's Disease: Treatment
257
Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
257
01:23Antidepressant Drugs: MAOIs and Other Agents
220
Atypical antidepressants, including bupropion (Wellbutrin), mirtazapine (Remeron), nefazodone (Serzone), trazodone (Desyrel), and vilazodone (Viibryd), offer unique mechanisms of action. Bupropion weakly inhibits dopamine and norepinephrine reuptake, aiding depression treatment and smoking cessation, with a low risk of sexual dysfunction. Mirtazapine enhances serotonin and norepinephrine neurotransmission, leading to sedation, increased appetite, and weight gain. As a result, it helps treat...
220